Movement, imaging and neurobehavioral assessment as predictors of cerebral palsy in preterm infants.
Cast your vote
You can rate an item by clicking the amount of stars they wish to award to this item.
When enough users have cast their vote on this item, the average rating will also be shown.
Your vote was cast
Thank you for your feedback
Thank you for your feedback
MetadataShow full item record
AbstractOBJECTIVE: To study the relative efficacy of three early predictors of cerebral palsy. METHOD: One Hundred and thirty infants with birth weight <1500 g were recruited. Video recordings of spontaneous general movements were made at 36 and 52 weeks postconceptional age. Magnetic resonance imaging and the neurobehavioral assessment of the preterm infant were done at 36 weeks postconceptional age. Follow-up neurological examination and Bayley assessments were made at 18 months corrected age to make early identification of cerebral palsy. RESULTS: Magnetic resonance imaging gave the best specificity and accuracy of 91 and 84% respectively. General movements at 52 weeks showed an improved specificity and accuracy over performance at 36 weeks postconceptional age. The negative predictive value for all methods tested was between 90 and 97%. Combining the results of magnetic resonance imaging and the neurobehavioral assessment improved the sensitivity of prediction to 80%, suggesting that a holistic approach to early detection of cerebral lesions is preferable to a single test. CONCLUSIONS: The majority of infants who appeared to behave within normal limits and exhibit normal brain structure in the newborn period were classified as neurologically intact at follow-up.
CitationJournal of Perinatology, 27(4): 225-229
PublisherNature Publishing Group
- Predicting motor development in very preterm infants at 12 months' corrected age: the role of qualitative magnetic resonance imaging and general movements assessments.
- Authors: Spittle AJ, Boyd RN, Inder TE, Doyle LW
- Issue date: 2009 Feb
- Predictive value of assessment of general movements for neurological development of high-risk preterm infants: comparative study.
- Authors: Seme-Ciglenecki P
- Issue date: 2003 Dec
- Does the assessment of general movements without video observation reliably predict neurological outcome?
- Authors: Guzzetta A, Belmonti V, Battini R, Boldrini A, Paolicelli PB, Cioni G
- Issue date: 2007 Nov
- Does a detailed assessment of poor repertoire general movements help to identify those infants who will develop normally?
- Authors: Nakajima Y, Einspieler C, Marschik PB, Bos AF, Prechtl HF
- Issue date: 2006 Jan
- Predictive value of neurodevelopmental assessment versus evaluation of general movements for motor outcome in preterm infants with birth weights <1500 g.
- Authors: Stahlmann N, Härtel C, Knopp A, Gehring B, Kiecksee H, Thyen U
- Issue date: 2007 Apr