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    Neurobehavioral assessment predicts differential outcome between VLBW and ELBW preterm infants.

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    Authors
    Constantinou, Janet C.
    Adamson-Macedo, Elvidina N.
    Mirmiran, Majid
    Ariagno, Ronald L.
    Fleisher, Barry E.
    Issue Date
    2005
    
    Metadata
    Show full item record
    Abstract
    OBJECTIVE: To evaluate the impact of birth weight on development of very low birth weight (VLBW) infants using the Neurobehavioral Assessment of the Preterm Infant (NAPI) before hospital discharge, and to show the relation to follow-up outcomes at 12, 18 and 30 months of age. STUDY DESIGN: In total, 113 preterm infants were assessed with the NAPI at 36 weeks postmenstrual age. Later, neurodevelopment was examined using the Bayley Infant Neurodevelopmental Screener (BINS) at 12 months and the Bayley Scales of Infant Development, at 18 and 30 months. The cohort was divided into two groups, based on birth weight, extremely low birth weight (ELBW) (<1000 g) and VLBW (1000 to 1500 g). RESULTS: ELBW infants showed significantly lower NAPI scores compared with VLBW infants at 36 weeks. The predischarge NAPI scores correlated with the 12, 18 and 30 months scores when the ELBW infants continue to have lower performance than the VLBW infants. In all, 14 infants developed cerebral palsy. These infants had significantly lower NAPI, BINS and Bayley scores compared with all other preterm infants. CONCLUSION: NAPI before discharge provides clinically meaningful information related to later neurodevelopmental outcome.
    Citation
    Journal of Perinatology, 25(12): 788-93
    Publisher
    Nature Publishing Group
    URI
    http://hdl.handle.net/2436/16713
    DOI
    10.1038/sj.jp.7211403
    PubMed ID
    16292337
    Additional Links
    http://www.nature.com/jp/journal/v25/n12/abs/7211403a.html
    Type
    Journal article
    Language
    en
    Description
    Metadata only. Full text available at links above.
    ISSN
    0743-8346
    ae974a485f413a2113503eed53cd6c53
    10.1038/sj.jp.7211403
    Scopus Count
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    Faculty of Education, Health and Wellbeing

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