Neurobehavioral assessment predicts differential outcome between VLBW and ELBW preterm infants.
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Authors
Constantinou, Janet C.Adamson-Macedo, Elvidina N.
Mirmiran, Majid
Ariagno, Ronald L.
Fleisher, Barry E.
Issue Date
2005
Metadata
Show full item recordAbstract
OBJECTIVE: To evaluate the impact of birth weight on development of very low birth weight (VLBW) infants using the Neurobehavioral Assessment of the Preterm Infant (NAPI) before hospital discharge, and to show the relation to follow-up outcomes at 12, 18 and 30 months of age. STUDY DESIGN: In total, 113 preterm infants were assessed with the NAPI at 36 weeks postmenstrual age. Later, neurodevelopment was examined using the Bayley Infant Neurodevelopmental Screener (BINS) at 12 months and the Bayley Scales of Infant Development, at 18 and 30 months. The cohort was divided into two groups, based on birth weight, extremely low birth weight (ELBW) (<1000 g) and VLBW (1000 to 1500 g). RESULTS: ELBW infants showed significantly lower NAPI scores compared with VLBW infants at 36 weeks. The predischarge NAPI scores correlated with the 12, 18 and 30 months scores when the ELBW infants continue to have lower performance than the VLBW infants. In all, 14 infants developed cerebral palsy. These infants had significantly lower NAPI, BINS and Bayley scores compared with all other preterm infants. CONCLUSION: NAPI before discharge provides clinically meaningful information related to later neurodevelopmental outcome.Citation
Journal of Perinatology, 25(12): 788-93Publisher
Nature Publishing GroupPubMed ID
16292337Additional Links
http://www.nature.com/jp/journal/v25/n12/abs/7211403a.htmlType
Journal articleLanguage
enDescription
Metadata only. Full text available at links above.ISSN
0743-8346ae974a485f413a2113503eed53cd6c53
10.1038/sj.jp.7211403
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