Disease activity and low physical activity associate with number of hospital admissions and length of hospitalisation in patients with rheumatoid arthritis
Authors
Metsios, George S.Stavropoulos-Kalinoglou, Antonios
Treharne, Gareth J.
Nevill, Alan M.
Sandoo, Aamer
Panoulas, Vasileios F.
Toms, Tracey E.
Koutedakis, Yiannis
Kitas, George D.
Issue Date
2011
Metadata
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ABSTRACT: INTRODUCTION: Substantial effort has been devoted to devising effective and safe interventions to reduce preventable hospital admissions in chronic disease patients. In rheumatoid arthritis (RA), identifying risk factors for admission have important health policy implications, but knowledge of which factors cause or prevent hospital admissions is currently lacking. We hypothesised that disease activity/severity and physical activity are major predictors for the need of hospitalisation in patients with RA. METHODS: 244 RA patients were assessed for: physical activity (international physical activity questionnaire), RA activity (C-reactive protein: CRP; disease activity score: DAS28) and disability (health assessment questionnaire: HAQ). Number of hospital admissions and length of hospitalisation within a year from baseline assessment was collected prospectively. RESULTS: Disease activity and disability as well as levels of overall and intensive physical activity levels correlated significantly with both the number of admissions and length of hospitalisation (p<0.05); regression analyses revealed that only disease activity (DAS28) and physical activity were significant independent predictors of numbers of hospital admissions [DAS28: (exp(B)=1.795, p=0.002 and physical activity: (exp(B)=0.999, p=0.046)) and length of hospitalisation [DAS28: (exp(B)=1.795, p=0.002 and physical activity: (exp(B)=0.999, p=0.046). Sub-analysis of the data demonstrated that only 19% (n=49) of patients engaged in recommended levels of physical activity. CONCLUSIONS: This study provides evidence that physical activity, along with disease activity, are important predictors of the number of hospital admissions and length of hospitalisation in RA. The combination of lifestyle changes, particularly increased physical activity, along with effective pharmacological therapy, may improve multiple health outcomes as well as cost of care for RA patients.Citation
Arthritis research & therapy, 13(3)Journal
Arthritis Research & TherapyDOI
10.1186/ar3390PubMed ID
21714856Type
Journal articleLanguage
enDescription
Epub ahead of printISSN
1478-6362ae974a485f413a2113503eed53cd6c53
10.1186/ar3390
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