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Multi-channel photonic crystal fiber based surface plasmon resonance sensor for multi-analyte sensing© 2009-2012 IEEE. In this paper, we report a unique multi-channel Photonic Crystal Fibre (PCF) sensor based on Surface Plasmon Resonance (SPR) structure comprising of silver and gold doped plasmonic layers for multi-Analyte sensing applications. We deployed a Full Vectorial Finite Element Method (FV-FEM) to investigate the sensitivity performance of the proposed PCF sensor. The SPR sensor is fully optimised to ensure propagation features, such as confinement loss, resonance condition, resolution and sensitivity are investigated within various optimised design parameters. According to spectral sensitivity analyses, 2500 nm/RIU and 3083 nm/RIU with 4 × 10-5 RIU and 3.2 × 10-5 RIU resolutions are obtained for Channel 1 (Ch1) (x-polarized) and Channel 2 (Ch2) (y-polarized), respectively.