• Admin Login
    View Item 
    •   Home
    • Faculty of Education, Health and Wellbeing
    • Faculty of Education, Health and Wellbeing
    • View Item
    •   Home
    • Faculty of Education, Health and Wellbeing
    • Faculty of Education, Health and Wellbeing
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of WIRECommunitiesTitleAuthorsIssue DateSubmit DateSubjectsTypesJournalDepartmentPublisherThis CollectionTitleAuthorsIssue DateSubmit DateSubjectsTypesJournalDepartmentPublisher

    Administrators

    Admin Login

    Local Links

    AboutThe University LibraryOpen Access Publications PolicyDeposit LicenceCOREWIRE Copyright and Reuse Information

    Statistics

    Display statistics

    Immediate and short-term consequences of secondhand smoke exposure on the respiratory system.

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Authors
    Flouris, Andreas D.
    Koutedakis, Yiannis
    Issue Date
    2011
    
    Metadata
    Show full item record
    Abstract
    Purpose of review This review critically evaluates the existing biological evidence regarding the immediate and short-term respiratory consequences of secondhand smoke (SHS). Recent findings A 1-h exposure to SHS at bar/restaurant levels generates a marked inflammatory reaction and significant decrements on lung function. These deleterious effects of SHS are exacerbated when physical activity follows the SHS exposure, particularly in less fit individuals. The main respiratory effect mechanisms of SHS include a direct induction of growth factors resulting in airway remodelling and alterations in nitric oxide regulation. Pharmacological agents that increase either apical membrane chloride conductance or basolateral membrane potassium conductance may be of therapeutic benefit in patients with diseases related to SHS exposure. Moreover, treatment with statins has shown beneficial effects towards preventing the SHS-induced pulmonary hypertension, vascular remodelling, and endothelial dysfunction. Summary Based on recently discovered evidence, even brief and short-term exposures to SHS generate significant adverse effects on the human respiratory system. Future research directions in this area include the concentrations of tobacco smoke constituents in the alveolar milieu following SHS exposure, individual susceptibility to SHS, as well as pharmacological treatments for reversing the SHS-induced airway remodelling.
    Citation
    Current opinion in pulmonary medicine, 17(2):110-5
    Publisher
    Lippincott Williams & Wilkins
    Journal
    Current opinion in pulmonary medicine
    URI
    http://hdl.handle.net/2436/129495
    DOI
    10.1097/MCP.0b013e328343165d
    PubMed ID
    21178628
    Type
    Journal article
    Language
    en
    ISSN
    1070-5287
    ae974a485f413a2113503eed53cd6c53
    10.1097/MCP.0b013e328343165d
    Scopus Count
    Collections
    Faculty of Education, Health and Wellbeing

    entitlement

    Related articles

    • Secondhand smoke exposure, pulmonary function, and cardiovascular mortality.
    • Authors: Eisner MD, Wang Y, Haight TJ, Balmes J, Hammond SK, Tager IB
    • Issue date: 2007 May
    • Passive smoking: is it harmful ?
    • Authors: Martin P
    • Issue date: 1986 Aug 13
    • Association between respiratory tract diseases and secondhand smoke exposure among never smoking flight attendants: a cross-sectional survey.
    • Authors: Ebbert JO, Croghan IT, Schroeder DR, Murawski J, Hurt RD
    • Issue date: 2007 Sep 26
    • Exposure to secondhand smoke and academic performance in non-smoking adolescents.
    • Authors: Ho SY, Lai HK, Wang MP, Lam TH
    • Issue date: 2010 Dec
    • The impact of secondhand smoke on children: respiratory and other medical concerns.
    • Authors: Lounsbery MG, Bubak ME
    • Issue date: 2009
    DSpace software (copyright © 2002 - 2023)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.