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    Cardiorespiratory measurements during field tests in CF: Use of an ambulatory monitoring system

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    Authors
    Bradley, Judy M.
    Kent, Lisa
    O'Neill, Brenda
    Nevill, Alan M.
    Boyle, Lesley
    Elborn, J. Stuart
    Issue Date
    2010
    
    Metadata
    Show full item record
    Abstract
    Respiratory inductive plethysmography (e.g., LifeShirt) may offer in-depth study of the cardiorespiratory responses during field exercise tests. The aims of this study were to assess the reliability, discriminate validity, and responsiveness of cardiorespiratory measurements recorded by the LifeShirt during field exercise tests in adults with CF. To assess reliability and discriminate validity, participants with CF and stable lung disease and healthy participants performed the 6-Minute Walk Test (6MWT) and Modified Shuttle Test (MST) on two occasions. To assess responsiveness, participants with CF experiencing an exacerbation performed the 6MWT at the start and end of an admission for intravenous antibiotics. The LifeShirt was worn during all exercise tests. Reliability and discriminate validity were assessed in 18 participants with CF (mean (SD) age: 26 (10) years; FEV1 %predicted: 69.2 (23)%) and 18 healthy participants (age: 24 (5) years, FEV1 %predicted: 92 (8)%). There was no difference in 6MWT and MST performance between days and reliability of cardiorespiratory measures was acceptable (bias: P > 0.05; CV < 10%). Participants with CF demonstrated a significantly greater response to exercise (e.g., ventilation, respiratory rate) compared to healthy participants indicating discriminate validity. Responsiveness was assessed in 12 participants with CF: clinical measurements and 6MWT performance improved (61 (81) min; P < 0.05) however, cardiorespiratory measurements recorded by the LifeShirt remained the same (bias: P > 0.05; CV < 10%). This study provides evidence that cardiorespiratory responses can be measured non-invasively during field exercise tests in adults with CF. Reliability and discriminate validity of key cardiorespiratory measurements recorded by the LifeShirt were demonstrated. Some information on responsiveness is reported.
    Citation
    Pediatric Pulmonology
    Publisher
    Wiley-Liss
    Journal
    Pediatric Pulmonology
    URI
    http://hdl.handle.net/2436/116843
    DOI
    10.1002/ppul.21360
    Additional Links
    http://doi.wiley.com/10.1002/ppul.21360
    Type
    Journal article
    Language
    en
    Description
    Article first published online: 21 OCT 2010
    ISSN
    87556863
    ae974a485f413a2113503eed53cd6c53
    10.1002/ppul.21360
    Scopus Count
    Collections
    Faculty of Education, Health and Wellbeing

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