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Wolverhampton Intellectual Repository and E-Theses > Research Institutes > Research Institute in Healthcare Science > Molecular Pharmacology Research Group > Pressurized liquid extraction of active ingredients (ginsenosides) from medicinal plants using non-ionic surfactant solutions.

Please use this identifier to cite or link to this item: http://hdl.handle.net/2436/9854
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Title: Pressurized liquid extraction of active ingredients (ginsenosides) from medicinal plants using non-ionic surfactant solutions.
Authors: Choi, Maggie P.K.
Chan, Kelvin C.
Leung, Hei Wun
Huie, Carmen W.
Citation: Journal of Chromatography A, 983(1-2): 153-162
Publisher: Elsevier
Issue Date: 2003
URI: http://hdl.handle.net/2436/9854
DOI: 10.1016/S0021-9673(02)01649-7
PubMed ID: 12568379
Additional Links: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TG8-47C8S2K-1&_user=1644469&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000054077&_version=1&_urlVersion=0&_userid=1644469&md5=18c537a43860e3b2f32236012954ba4f
Abstract: The feasibility of employing aqueous non-ionic surfactant solutions as an alternative solvent system in pressurized liquid extraction (PLE) is demonstrated for the first time using the roots of American ginseng as model solid samples. When compared to the use of pure water or methanol, the presence of a common non-ionic surfactant (Triton X-100) in water at a concentration above its critical micelle concentration was shown to enhance the amount of pharmacologically active ingredients (ginsenosides) extracted from ginseng roots. The advantages of using aqueous non-surfactant solutions were also demonstrated by comparing extraction performances between ultrasonic-assisted extraction and PLE methods. Furthermore, the combination of PLE and cloud point extraction was shown to be a new and effective approach for the rapid sample preconcentration of herbal materials prior to analysis by high-performance liquid chromatography.
Type: Article
Language: en
Keywords: Ginsenosides
Surfactants
Pressurized liquid extraction
Saponins
ISSN: 0021-9673
Appears in Collections: Molecular Pharmacology Research Group

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