Pressurized liquid extraction of active ingredients (ginsenosides) from medicinal plants using non-ionic surfactant solutions.

2.50
Hdl Handle:
http://hdl.handle.net/2436/9854
Title:
Pressurized liquid extraction of active ingredients (ginsenosides) from medicinal plants using non-ionic surfactant solutions.
Authors:
Choi, Maggie P.K.; Chan, Kelvin C.; Leung, Hei Wun; Huie, Carmen W.
Abstract:
The feasibility of employing aqueous non-ionic surfactant solutions as an alternative solvent system in pressurized liquid extraction (PLE) is demonstrated for the first time using the roots of American ginseng as model solid samples. When compared to the use of pure water or methanol, the presence of a common non-ionic surfactant (Triton X-100) in water at a concentration above its critical micelle concentration was shown to enhance the amount of pharmacologically active ingredients (ginsenosides) extracted from ginseng roots. The advantages of using aqueous non-surfactant solutions were also demonstrated by comparing extraction performances between ultrasonic-assisted extraction and PLE methods. Furthermore, the combination of PLE and cloud point extraction was shown to be a new and effective approach for the rapid sample preconcentration of herbal materials prior to analysis by high-performance liquid chromatography.
Citation:
Journal of Chromatography A, 983(1-2): 153-162
Publisher:
Elsevier
Issue Date:
2003
URI:
http://hdl.handle.net/2436/9854
DOI:
10.1016/S0021-9673(02)01649-7
PubMed ID:
12568379
Additional Links:
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TG8-47C8S2K-1&_user=1644469&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000054077&_version=1&_urlVersion=0&_userid=1644469&md5=18c537a43860e3b2f32236012954ba4f
Submitted date:
2007-02-07
Type:
Article
Language:
en
ISSN:
0021-9673
Appears in Collections:
Molecular Pharmacology Research Group

Full metadata record

DC FieldValue Language
dc.contributor.authorChoi, Maggie P.K.-
dc.contributor.authorChan, Kelvin C.-
dc.contributor.authorLeung, Hei Wun-
dc.contributor.authorHuie, Carmen W.-
dc.date.accessioned2007-03-07T15:03:33Z-
dc.date.available2007-03-07T15:03:33Z-
dc.date.issued2003-
dc.date.submitted2007-02-07-
dc.identifier.citationJournal of Chromatography A, 983(1-2): 153-162en
dc.identifier.issn0021-9673-
dc.identifier.pmid12568379-
dc.identifier.doi10.1016/S0021-9673(02)01649-7-
dc.identifier.urihttp://hdl.handle.net/2436/9854-
dc.description.abstractThe feasibility of employing aqueous non-ionic surfactant solutions as an alternative solvent system in pressurized liquid extraction (PLE) is demonstrated for the first time using the roots of American ginseng as model solid samples. When compared to the use of pure water or methanol, the presence of a common non-ionic surfactant (Triton X-100) in water at a concentration above its critical micelle concentration was shown to enhance the amount of pharmacologically active ingredients (ginsenosides) extracted from ginseng roots. The advantages of using aqueous non-surfactant solutions were also demonstrated by comparing extraction performances between ultrasonic-assisted extraction and PLE methods. Furthermore, the combination of PLE and cloud point extraction was shown to be a new and effective approach for the rapid sample preconcentration of herbal materials prior to analysis by high-performance liquid chromatography.en
dc.format.extent470818 bytes-
dc.format.mimetypeapplication/pdf-
dc.language.isoenen
dc.publisherElsevieren
dc.relation.urlhttp://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TG8-47C8S2K-1&_user=1644469&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000054077&_version=1&_urlVersion=0&_userid=1644469&md5=18c537a43860e3b2f32236012954ba4fen
dc.subjectGinsenosidesen
dc.subjectSurfactantsen
dc.subjectPressurized liquid extractionen
dc.subjectSaponinsen
dc.titlePressurized liquid extraction of active ingredients (ginsenosides) from medicinal plants using non-ionic surfactant solutions.en
dc.typeArticleen
dc.format.digYES-
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