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Wolverhampton Intellectual Repository and E-Theses > Research Institutes > Research Institute in Healthcare Science > Molecular Pharmacology Research Group > Quality control of herbal medicines.

Please use this identifier to cite or link to this item: http://hdl.handle.net/2436/9853
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Title: Quality control of herbal medicines.
Authors: Liang, Yi-Zeng
Xie, Peishan
Chan, Kelvin C.
Citation: Journal of Chromatography B, 812(1-2): 53-70
Publisher: Elsevier
Issue Date: 2004
URI: http://hdl.handle.net/2436/9853
DOI: 10.1016/j.jchromb.2004.08.041
PubMed ID: 15556488
Additional Links: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6X0P-4DCWC5R-1&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=2206b8c5c3f1ee0356d6fc4092f32d6b
Abstract: Different chromatographic and electrophoretic techniques commonly used in the instrumental inspection of herbal medicines (HM) are first comprehensively reviewed. Chemical fingerprints obtained by chromatographic and electrophoretic techniques, especially by hyphenated chromatographies, are strongly recommended for the purpose of quality control of herbal medicines, since they might represent appropriately the "chemical integrities" of the herbal medicines and therefore be used for authentication and identification of the herbal products. Based on the conception of phytoequivalence, the chromatographic fingerprints of herbal medicines could be utilized for addressing the problem of quality control of herbal medicines. Several novel chemometric methods for evaluating the fingerprints of herbal products, such as the method based on information theory, similarity estimation, chemical pattern recognition, spectral correlative chromatogram (SCC), multivariate resolution, etc. are discussed in detail with examples, which showed that the combination of chromatographic fingerprints of herbal medicines and the chemometric evaluation might be a powerful tool for quality control of herbal products.
Type: Article
Language: en
Keywords: Herbal medicine
Chromatographic fingerprints
Quality Control
Chemometrics
Plants, Medicinal
ISSN: 1570-0232
Appears in Collections: Molecular Pharmacology Research Group

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