Study on Angelica and its different extracts by Fourier transform infrared spectroscopy and two-dimensional correlation IR spectroscopy.

2.50
Hdl Handle:
http://hdl.handle.net/2436/9832
Title:
Study on Angelica and its different extracts by Fourier transform infrared spectroscopy and two-dimensional correlation IR spectroscopy.
Authors:
Liu, Hong-xia; Sun, Su-qin; Lu, Guang-Hua; Chan, Kelvin C.
Abstract:
In order to develop a rapid and effective analysis method for studying integrally the main constituents in the medicinal materials and their extracts, discriminating the extracts from different extraction process, comparing the categories of chemical constituents in the different extracts and monitoring the qualities of medicinal materials, we applied Fourier transform infrared spectroscopy (FT-IR) associated with second derivative infrared spectroscopy and two-dimensional correlation infrared spectroscopy (2D-IR) to study the main constituents in traditional Chinese medicine Angelica and its different extracts (extracted by petroleum ether, ethanol and water in turn). The findings indicated that FT-IR spectrum can provide many holistic variation rules of chemical constituents. Use of the macroscopical fingerprint characters of FT-IR and 2D-IR spectrum can not only identify the main chemical constituents in medicinal materials and their different extracts, but also compare the components differences among the similar samples. This analytical method is highly rapid, effective, visual and accurate for pharmaceutical research.
Citation:
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 64(2): 321-326
Publisher:
Elsevier
Issue Date:
2006
URI:
http://hdl.handle.net/2436/9832
DOI:
10.1016/j.saa.2005.07.026
PubMed ID:
16386456
Additional Links:
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6VNG-4HX47S7-2&_user=1644469&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000054077&_version=1&_urlVersion=0&_userid=1644469&md5=96b2744837e2c0202a570ef1599391f7
Submitted date:
2007-02-01
Type:
Article
Language:
en
ISSN:
1386-1425
Appears in Collections:
Molecular Pharmacology Research Group

Full metadata record

DC FieldValue Language
dc.contributor.authorLiu, Hong-xia-
dc.contributor.authorSun, Su-qin-
dc.contributor.authorLu, Guang-Hua-
dc.contributor.authorChan, Kelvin C.-
dc.date.accessioned2007-03-07T13:47:47Z-
dc.date.available2007-03-07T13:47:47Z-
dc.date.issued2006-
dc.date.submitted2007-02-01-
dc.identifier.citationSpectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 64(2): 321-326en
dc.identifier.issn1386-1425-
dc.identifier.pmid16386456-
dc.identifier.doi10.1016/j.saa.2005.07.026-
dc.identifier.urihttp://hdl.handle.net/2436/9832-
dc.description.abstractIn order to develop a rapid and effective analysis method for studying integrally the main constituents in the medicinal materials and their extracts, discriminating the extracts from different extraction process, comparing the categories of chemical constituents in the different extracts and monitoring the qualities of medicinal materials, we applied Fourier transform infrared spectroscopy (FT-IR) associated with second derivative infrared spectroscopy and two-dimensional correlation infrared spectroscopy (2D-IR) to study the main constituents in traditional Chinese medicine Angelica and its different extracts (extracted by petroleum ether, ethanol and water in turn). The findings indicated that FT-IR spectrum can provide many holistic variation rules of chemical constituents. Use of the macroscopical fingerprint characters of FT-IR and 2D-IR spectrum can not only identify the main chemical constituents in medicinal materials and their different extracts, but also compare the components differences among the similar samples. This analytical method is highly rapid, effective, visual and accurate for pharmaceutical research.en
dc.format.extent440400 bytes-
dc.format.mimetypeapplication/pdf-
dc.language.isoenen
dc.publisherElsevieren
dc.relation.urlhttp://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6VNG-4HX47S7-2&_user=1644469&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000054077&_version=1&_urlVersion=0&_userid=1644469&md5=96b2744837e2c0202a570ef1599391f7en
dc.subjectAngelicaen
dc.subjectFourier transform infrared spectroscopyen
dc.subjectFT-IRen
dc.subjectChinese medicineen
dc.titleStudy on Angelica and its different extracts by Fourier transform infrared spectroscopy and two-dimensional correlation IR spectroscopy.en
dc.typeArticleen
dc.format.digYES-
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