2.50
Hdl Handle:
http://hdl.handle.net/2436/7746
Title:
Antioxidants and AP-1 activation: a brief overview.
Authors:
Gómez del Arco, Pablo; Martínez-Martínez, Sara; Calvo, Victor; Armesilla, Angel Luis; Redondo, Juan Miguel
Abstract:
Activity of the transcription factor AP-1 is controlled by different MAPK cascades that regulate the different AP-1 components at the transcriptional and posttranscriptional level. Recently, AP-1 has been shown to behave as a redox-sensitive transcription factor that can be induced under both pro-oxidative and antioxidative conditions. In this overview we summarize the signaling pathways that converge on the activation of AP-1 and the components of these pathways that have been shown to be targets of antioxidants. The activation of AP-1 by antioxidants may account for the expression of a number of genes that mediate important functions under physiological conditions.
Citation:
Immunobiology, 198(1-3): 273-278
Publisher:
Elsevier BV
Issue Date:
1997
URI:
http://hdl.handle.net/2436/7746
PubMed ID:
9442398
Additional Links:
http://cat.inist.fr/?aModele=afficheN&cpsidt=10321900; http://direct.bl.uk/bld/PlaceOrder.do?UIN=037406284&ETOC=RN&from=searchengine
Submitted date:
2007-01-24
Type:
Article
Language:
en
Description:
Metadata only
ISSN:
0171-2985
Appears in Collections:
Molecular Pharmacology Research Group

Full metadata record

DC FieldValue Language
dc.contributor.authorGómez del Arco, Pablo-
dc.contributor.authorMartínez-Martínez, Sara-
dc.contributor.authorCalvo, Victor-
dc.contributor.authorArmesilla, Angel Luis-
dc.contributor.authorRedondo, Juan Miguel-
dc.date.accessioned2007-01-24T14:45:23Z-
dc.date.available2007-01-24T14:45:23Z-
dc.date.issued1997-
dc.date.submitted2007-01-24-
dc.identifier.citationImmunobiology, 198(1-3): 273-278en
dc.identifier.issn0171-2985-
dc.identifier.pmid9442398-
dc.identifier.urihttp://hdl.handle.net/2436/7746-
dc.descriptionMetadata onlyen
dc.description.abstractActivity of the transcription factor AP-1 is controlled by different MAPK cascades that regulate the different AP-1 components at the transcriptional and posttranscriptional level. Recently, AP-1 has been shown to behave as a redox-sensitive transcription factor that can be induced under both pro-oxidative and antioxidative conditions. In this overview we summarize the signaling pathways that converge on the activation of AP-1 and the components of these pathways that have been shown to be targets of antioxidants. The activation of AP-1 by antioxidants may account for the expression of a number of genes that mediate important functions under physiological conditions.en
dc.language.isoenen
dc.publisherElsevier BVen
dc.relation.urlhttp://cat.inist.fr/?aModele=afficheN&cpsidt=10321900en
dc.relation.urlhttp://direct.bl.uk/bld/PlaceOrder.do?UIN=037406284&ETOC=RN&from=searchengine-
dc.subjectTranscription factoren
dc.subjectAP-1en
dc.subjectAntioxidantsen
dc.titleAntioxidants and AP-1 activation: a brief overview.en
dc.typeArticleen
dc.format.digYES-

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