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Modelling the influence of age, body size and sex on maximum oxygen uptake in older humans.
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|Title: ||Modelling the influence of age, body size and sex on maximum oxygen uptake in older humans.|
|Affiliation: ||Department of Exercise Physiology, De Montfort University Bedford, Bedford MK40 2BZ, UK.|
|Citation: ||Experimental physiology 2000, 85 (2):219-25|
|Publisher: ||The Physiological Society|
|Journal: ||Experimental physiology|
|Issue Date: ||Mar-2000 |
|PubMed ID: ||10751519|
|Additional Links: ||http://ep.physoc.org/content/85/2/219.abstract|
|Abstract: ||The purpose of this study was to describe the influence of body size and sex on the decline in maximum oxygen uptake (O2,max) in older men and women. A stratified random sample of 152 men and 146 women, aged 55-86 years, was drawn from the study population. Influence of age on O2,max, independent of differences in body mass (BM) or fat-free mass (FFM), was investigated using the following allometric model: O2,max = BMb (or FFMb) exp(a + (c ' age) + (d ' sex)) [epsilon]. The model was linearised and parameters identified using standard multiple regression. The BM model explained 68.8 % of the variance in O2,max. The parameters (+/- s.e.e., standard error of the estimate) for lnBM (0.563 +/- 0.070), age (-0.0154 +/- 0.0012), sex (0.242 +/- 0.024) and the intercept (-1.09 +/- 0.32) were all significant (P < 0.001). The FFM model explained 69.3 % of the variance in O2,max, and the parameters (+/- s.e.e) lnFFM (0.772 +/- 0.090), age (-0.0159 +/- 0.0012) and the intercept (-1.57 +/- 0.36) were significant (P < 0.001), while sex (0.077 +/- 0.038) was significant at P = 0.0497. Regardless of the model used, the age-associated decline was similar, with a relative decline of 15 % per decade (0.984 exp(age)) in O2,max in older humans being estimated. The study has demonstrated that, for a randomly drawn sample, the age-related loss in O2,max is determined, in part, by the loss of fat-free body mass. When this factor is accounted for, the loss of O2,max across age is similar in older men and women.|
Aged, 80 and over
|Appears in Collections: ||Sport, Exercise and Health Research Group|
Learning and Teaching in Sport, Exercise and Performance
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