Cardio-respiratory fitness, habitual physical activity and serum brain derived neurotrophic factor (BDNF) in men and women

2.50
Hdl Handle:
http://hdl.handle.net/2436/74774
Title:
Cardio-respiratory fitness, habitual physical activity and serum brain derived neurotrophic factor (BDNF) in men and women
Authors:
Currie, James; Ramsbottom, Roger; Ludlow, Helen; Nevill, Alan M.; Gilder, Michael
Abstract:
Short episodes of high intensity exercise transiently increase serum levels of BDNF in humans, but serum levels of BDNF at rest appear to be lower in more physically active humans with greater levels of energy expenditure. The relationship between serum BDNF concentration, cardio-respiratory fitness (Åstrand–Rhyming test estimated VO2 max) and volume of long-term, regular exercise and sporting activity (Baecke Habitual Physical Activity Index) was investigated in 44 men and women between the age range of 18–57 years. In this group an inverse relationship between resting serum BDNF concentration and measures of both estimated VO2 max (r =−0.352; P < 0.05) and long-term sporting activity (r =−0.428, P < 0.01) was found. These results indicate that increased levels of cardio-respiratory fitness and habitual exercise are associated with lower resting levels of serum BDNF in healthy humans. This is the first study to demonstrate an inverse relationship between a physiological estimate of cardio-respiratory fitness and serum BDNF.
Citation:
Neuroscience Letters 451 (2009) 152–155
Journal:
Neuroscience Letters
Issue Date:
2009
URI:
http://hdl.handle.net/2436/74774
DOI:
10.1016/j.neulet.2008.12.043
Additional Links:
http://www.elsevier.com/wps/find/journaldescription.cws_home/506081/description#description
Type:
Article
Language:
en
ISSN:
0304-3940
Appears in Collections:
Sport, Exercise and Health Research Group; Learning and Teaching in Sport, Exercise and Performance

Full metadata record

DC FieldValue Language
dc.contributor.authorCurrie, James-
dc.contributor.authorRamsbottom, Roger-
dc.contributor.authorLudlow, Helen-
dc.contributor.authorNevill, Alan M.-
dc.contributor.authorGilder, Michael-
dc.date.accessioned2009-07-21T14:23:04Z-
dc.date.available2009-07-21T14:23:04Z-
dc.date.issued2009-
dc.identifier.citationNeuroscience Letters 451 (2009) 152–155en
dc.identifier.issn0304-3940-
dc.identifier.doi10.1016/j.neulet.2008.12.043-
dc.identifier.urihttp://hdl.handle.net/2436/74774-
dc.description.abstractShort episodes of high intensity exercise transiently increase serum levels of BDNF in humans, but serum levels of BDNF at rest appear to be lower in more physically active humans with greater levels of energy expenditure. The relationship between serum BDNF concentration, cardio-respiratory fitness (Åstrand–Rhyming test estimated VO2 max) and volume of long-term, regular exercise and sporting activity (Baecke Habitual Physical Activity Index) was investigated in 44 men and women between the age range of 18–57 years. In this group an inverse relationship between resting serum BDNF concentration and measures of both estimated VO2 max (r =−0.352; P < 0.05) and long-term sporting activity (r =−0.428, P < 0.01) was found. These results indicate that increased levels of cardio-respiratory fitness and habitual exercise are associated with lower resting levels of serum BDNF in healthy humans. This is the first study to demonstrate an inverse relationship between a physiological estimate of cardio-respiratory fitness and serum BDNF.en
dc.language.isoenen
dc.relation.urlhttp://www.elsevier.com/wps/find/journaldescription.cws_home/506081/description#descriptionen
dc.subjectBDNFen
dc.subjectEstimated VO2 maxen
dc.subjectPhysical activityen
dc.subjectHumanen
dc.titleCardio-respiratory fitness, habitual physical activity and serum brain derived neurotrophic factor (BDNF) in men and womenen
dc.typeArticleen
dc.identifier.journalNeuroscience Lettersen
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