Quantitative analysis of malondialdehyde-guanine adducts in genomic DNA samples by liquid chromatography/tandem mass spectrometry.

2.50
Hdl Handle:
http://hdl.handle.net/2436/621014
Title:
Quantitative analysis of malondialdehyde-guanine adducts in genomic DNA samples by liquid chromatography/tandem mass spectrometry.
Authors:
Yates, Sally A; Dempster, Nicola M; Murphy, Mark F; Moore, Sharon A
Abstract:
The lipid peroxidation product malondialdehyde forms M1 dG adducts with guanine bases in genomic DNA. The analysis of these adducts is important as a biomarker of lipid peroxidation, oxidative stress and inflammation which may be linked to disease risk or exposure to a range of chemicals.
Citation:
Quantitative analysis of malondialdehyde-guanine adducts in genomic DNA samples by liquid chromatography/tandem mass spectrometry. 2017, 31 (9):762-770 Rapid Commun. Mass Spectrom.
Publisher:
Wiley
Journal:
Rapid communications in mass spectrometry : RCM
Issue Date:
16-May-2017
URI:
http://hdl.handle.net/2436/621014
DOI:
10.1002/rcm.7843
PubMed ID:
28231608
Type:
Article
Language:
en
Appears in Collections:
FSE

Full metadata record

DC FieldValue Language
dc.contributor.authorYates, Sally Aen
dc.contributor.authorDempster, Nicola Men
dc.contributor.authorMurphy, Mark Fen
dc.contributor.authorMoore, Sharon Aen
dc.date.accessioned2017-12-20T16:54:08Z-
dc.date.available2017-12-20T16:54:08Z-
dc.date.issued2017-05-16-
dc.identifier.citationQuantitative analysis of malondialdehyde-guanine adducts in genomic DNA samples by liquid chromatography/tandem mass spectrometry. 2017, 31 (9):762-770 Rapid Commun. Mass Spectrom.en
dc.identifier.pmid28231608-
dc.identifier.doi10.1002/rcm.7843-
dc.identifier.urihttp://hdl.handle.net/2436/621014-
dc.description.abstractThe lipid peroxidation product malondialdehyde forms M1 dG adducts with guanine bases in genomic DNA. The analysis of these adducts is important as a biomarker of lipid peroxidation, oxidative stress and inflammation which may be linked to disease risk or exposure to a range of chemicals.en
dc.language.isoenen
dc.publisherWileyen
dc.rightsArchived with thanks to Rapid communications in mass spectrometry : RCMen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleQuantitative analysis of malondialdehyde-guanine adducts in genomic DNA samples by liquid chromatography/tandem mass spectrometry.en
dc.typeArticleen
dc.identifier.journalRapid communications in mass spectrometry : RCMen
dc.date.accepted2017-02-21-
rioxxterms.funderinternalen
rioxxterms.identifier.projectUOW201217en
rioxxterms.versionAMen
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/en
rioxxterms.licenseref.startdate2018-05-16en

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