Chronic l-menthol-induced browning of white adipose tissue hypothesis: A putative therapeutic regime for combating obesity and improving metabolic health.

2.50
Hdl Handle:
http://hdl.handle.net/2436/620758
Title:
Chronic l-menthol-induced browning of white adipose tissue hypothesis: A putative therapeutic regime for combating obesity and improving metabolic health.
Authors:
Sakellariou, Paraskevi; Valente, Angelica; Carrillo, Andres E; Metsios, George S; Nadolnik, Liliya; Jamurtas, Athanasios Z; Koutedakis, Yiannis; Boguszewski, Cesar; Andrade, Cláudia Marlise Balbinotti; Svensson, Per-Arne; Kawashita, Nair Honda; Flouris, Andreas D
Abstract:
Obesity constitutes a serious global health concern reaching pandemic prevalence rates. The existence of functional brown adipose tissue (BAT) in adult humans has provoked intense research interest in the role of this metabolically active tissue in whole-body energy balance and body weight regulation. A number of environmental, physiological, pathological, and pharmacological stimuli have been proposed to induce BAT-mediated thermogenesis and functional thermogenic BAT-like activity in white adipose tissue (WAT), opening new avenues for therapeutic strategies based on enhancing the number of beige adipocytes in WAT.
Citation:
Chronic l-menthol-induced browning of white adipose tissue hypothesis: A putative therapeutic regime for combating obesity and improving metabolic health. 2016, 93:21-6 Med. Hypotheses
Publisher:
Elsevier
Journal:
Medical hypotheses
Issue Date:
Aug-2016
URI:
http://hdl.handle.net/2436/620758
DOI:
10.1016/j.mehy.2016.05.006
PubMed ID:
27372851
Type:
Article
Language:
en
ISSN:
0306-9877
Appears in Collections:
Sport, Exercise and Health Research Group

Full metadata record

DC FieldValue Language
dc.contributor.authorSakellariou, Paraskevien
dc.contributor.authorValente, Angelicaen
dc.contributor.authorCarrillo, Andres Een
dc.contributor.authorMetsios, George Sen
dc.contributor.authorNadolnik, Liliyaen
dc.contributor.authorJamurtas, Athanasios Zen
dc.contributor.authorKoutedakis, Yiannisen
dc.contributor.authorBoguszewski, Cesaren
dc.contributor.authorAndrade, Cláudia Marlise Balbinottien
dc.contributor.authorSvensson, Per-Arneen
dc.contributor.authorKawashita, Nair Hondaen
dc.contributor.authorFlouris, Andreas Den
dc.date.accessioned2017-10-11T15:37:07Z-
dc.date.available2017-10-11T15:37:07Z-
dc.date.issued2016-08-
dc.identifier.citationChronic l-menthol-induced browning of white adipose tissue hypothesis: A putative therapeutic regime for combating obesity and improving metabolic health. 2016, 93:21-6 Med. Hypothesesen
dc.identifier.issn0306-9877en
dc.identifier.pmid27372851-
dc.identifier.doi10.1016/j.mehy.2016.05.006-
dc.identifier.urihttp://hdl.handle.net/2436/620758-
dc.description.abstractObesity constitutes a serious global health concern reaching pandemic prevalence rates. The existence of functional brown adipose tissue (BAT) in adult humans has provoked intense research interest in the role of this metabolically active tissue in whole-body energy balance and body weight regulation. A number of environmental, physiological, pathological, and pharmacological stimuli have been proposed to induce BAT-mediated thermogenesis and functional thermogenic BAT-like activity in white adipose tissue (WAT), opening new avenues for therapeutic strategies based on enhancing the number of beige adipocytes in WAT.en
dc.language.isoenen
dc.publisherElsevieren
dc.rightsArchived with thanks to Medical hypothesesen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectBrown adipose tissueen
dc.subjectMetabolismen
dc.subjectObesityen
dc.subjectOverweighten
dc.subjectTRPA1en
dc.subjectTRPM8en
dc.subjectThermogenesisen
dc.subjectUCP1en
dc.subjectWhite adipose tissueen
dc.subjectl-Mentholen
dc.subject.meshAdipose Tissue, Brown-
dc.subject.meshAdipose Tissue, White-
dc.subject.meshAnimals-
dc.subject.meshBody Weight-
dc.subject.meshComorbidity-
dc.subject.meshDiet-
dc.subject.meshEnergy Metabolism-
dc.subject.meshHumans-
dc.subject.meshMenthol-
dc.subject.meshModels, Theoretical-
dc.subject.meshObesity-
dc.subject.meshPhenotype-
dc.subject.meshPrevalence-
dc.subject.meshSignal Transduction-
dc.subject.meshTRPM Cation Channels-
dc.subject.meshThermogenesis-
dc.subject.meshUncoupling Protein 1-
dc.titleChronic l-menthol-induced browning of white adipose tissue hypothesis: A putative therapeutic regime for combating obesity and improving metabolic health.en
dc.typeArticleen
dc.identifier.journalMedical hypothesesen
dc.date.accepted2016-05-09-
rioxxterms.funderOpen Access funded by Brazilian Governmenten
rioxxterms.identifier.projectUOW111017YK3en
rioxxterms.versionVoRen
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/en
rioxxterms.licenseref.startdate2017-10-11en

Related articles on PubMed

This item is licensed under a Creative Commons License
Creative Commons
All Items in WIRE are protected by copyright, with all rights reserved, unless otherwise indicated.