Effect of a booster dose of influenza vaccine in patients with hemodialysis, peritoneal dialysis and renal transplant recipients: A systematic literature review and meta-analysis

2.50
Hdl Handle:
http://hdl.handle.net/2436/620517
Title:
Effect of a booster dose of influenza vaccine in patients with hemodialysis, peritoneal dialysis and renal transplant recipients: A systematic literature review and meta-analysis
Authors:
Liao, Zhengfa; Xu, Xiaojia; Liang, Yaping; Xiong, Yongzhen; Chen, Ruoling; Ni, Jindong
Abstract:
Booster influenza vaccination has been recommended for patients with chronic renal disease in order to enhance the immune response to the influenza vaccine; however, the efficacy of a booster influenza vaccination is a matter of controversy. Therefore, we made a meta-analysis to determine the efficacy in patients with hemodialysis (HD), peritoneal dialysis (PD) and renal transplant recipient (RT). The sero-protection rate was used as a serologic parameter to describe the immune response to the vaccine. Statistical analysis was performed to calculate the pooled rate difference (RD) and 95% confidence interval (CI). The pooled RD for the H1N1, H3N2 and B influenza vaccines was 0.02 (95% CI: −0.02–0.06), 0.05 (95% CI: −0.01–0.11), 0.04 (95% CI: −0.02–0.10), respectively. We concluded that a booster dose of the influenza vaccine did not effectively enhance immunogenicity. Therefore, a booster dose of vaccine is not recommended for patients with hemodialysis, peritoneal dialysis and renal transplant recipients.
Citation:
Effect of a booster dose of influenza vaccine in patients with hemodialysis, peritoneal dialysis and renal transplant recipients: A systematic literature review and meta-analysis 2016, 12 (11):2909 Human Vaccines & Immunotherapeutics
Publisher:
Taylor & Francis
Journal:
Human Vaccines & Immunotherapeutics
Issue Date:
8-Jul-2016
URI:
http://hdl.handle.net/2436/620517
DOI:
10.1080/21645515.2016.1201623
Additional Links:
https://www.tandfonline.com/doi/full/10.1080/21645515.2016.1201623
Type:
Article
Language:
en
ISSN:
2164-5515
Sponsors:
Natural Science Foundation of Guangdong Province, China
Appears in Collections:
FEHW

Full metadata record

DC FieldValue Language
dc.contributor.authorLiao, Zhengfaen
dc.contributor.authorXu, Xiaojiaen
dc.contributor.authorLiang, Yapingen
dc.contributor.authorXiong, Yongzhenen
dc.contributor.authorChen, Ruolingen
dc.contributor.authorNi, Jindongen
dc.date.accessioned2017-06-14T15:05:43Z-
dc.date.available2017-06-14T15:05:43Z-
dc.date.issued2016-07-08-
dc.identifier.citationEffect of a booster dose of influenza vaccine in patients with hemodialysis, peritoneal dialysis and renal transplant recipients: A systematic literature review and meta-analysis 2016, 12 (11):2909 Human Vaccines & Immunotherapeuticsen
dc.identifier.issn2164-5515en
dc.identifier.doi10.1080/21645515.2016.1201623-
dc.identifier.urihttp://hdl.handle.net/2436/620517-
dc.description.abstractBooster influenza vaccination has been recommended for patients with chronic renal disease in order to enhance the immune response to the influenza vaccine; however, the efficacy of a booster influenza vaccination is a matter of controversy. Therefore, we made a meta-analysis to determine the efficacy in patients with hemodialysis (HD), peritoneal dialysis (PD) and renal transplant recipient (RT). The sero-protection rate was used as a serologic parameter to describe the immune response to the vaccine. Statistical analysis was performed to calculate the pooled rate difference (RD) and 95% confidence interval (CI). The pooled RD for the H1N1, H3N2 and B influenza vaccines was 0.02 (95% CI: −0.02–0.06), 0.05 (95% CI: −0.01–0.11), 0.04 (95% CI: −0.02–0.10), respectively. We concluded that a booster dose of the influenza vaccine did not effectively enhance immunogenicity. Therefore, a booster dose of vaccine is not recommended for patients with hemodialysis, peritoneal dialysis and renal transplant recipients.en
dc.description.sponsorshipNatural Science Foundation of Guangdong Province, Chinaen
dc.language.isoenen
dc.publisherTaylor & Francisen
dc.relation.urlhttps://www.tandfonline.com/doi/full/10.1080/21645515.2016.1201623en
dc.rightsArchived with thanks to Human Vaccines & Immunotherapeuticsen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectEffectivenessen
dc.subjectInfluenza vaccineen
dc.subjecthemodialysisen
dc.subjectperitoneal dialysisen
dc.subjectrenal transplanten
dc.subjectrecipientsen
dc.subjectmeta-analysisen
dc.titleEffect of a booster dose of influenza vaccine in patients with hemodialysis, peritoneal dialysis and renal transplant recipients: A systematic literature review and meta-analysisen
dc.typeArticleen
dc.identifier.journalHuman Vaccines & Immunotherapeuticsen
dc.date.accepted2016-06-
rioxxterms.funderNatural Science Foundation of Guangdong Province, Chinaen
rioxxterms.identifier.projectUoW140617RCen
rioxxterms.versionAMen
rioxxterms.licenseref.urihttps://creativecommons.org/CC BY-NC-ND 4.0en
rioxxterms.licenseref.startdate2017-07-01en
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