Evaluation studies of a sensing technique for electrostatic charge polarity of pharmaceutical particulates

2.50
Hdl Handle:
http://hdl.handle.net/2436/605453
Title:
Evaluation studies of a sensing technique for electrostatic charge polarity of pharmaceutical particulates
Authors:
Kaialy, Waseem; Gorman, Terry; Hussain, Tariq; Armour-Chélu, David; Deng, Tong; Bradley, Michael Samuel Arthur
Abstract:
Electrostatic charge due to inter-particle and particle-wall contacts may generate significant hazards during the processing of particulates within the pharmaceutical industry. Although charge behaviour of particulates is erratic and not easy to predict, it would be desirable to characterise the tendency of tribocharging prior to manufacturing. The work reported in this paper concentrates on a new and novel techniques for the detection of the active ingredient and excipient in a bipolar material. Three different case studies are presented for demonstration of the applicability of the method in different practical situations. Work confirmed through an experimental rig set-up indicates that materials that accumulate opposite charge via contact and rubbing can be detected from their charge sign as well as their relative magnitude. The results reported clearly demonstrated that the developed method for charge characterisation is a useful tool to understand how the charges are distributed in a population of particles showing a number of advantages over conventional methods.
Citation:
Evaluation studies of a sensing technique for electrostatic charge polarity of pharmaceutical particulates 2016 IET Science, Measurement & Technology
Publisher:
IET Digital Library
Journal:
IET Science, Measurement & Technology
Issue Date:
15-Mar-2016
URI:
http://hdl.handle.net/2436/605453
DOI:
10.1049/iet-smt.2015.0194
Additional Links:
http://digital-library.theiet.org/content/journals/10.1049/iet-smt.2015.0194
Type:
Article
Language:
en
ISSN:
1751-8822; 1751-8830
Appears in Collections:
FSE

Full metadata record

DC FieldValue Language
dc.contributor.authorKaialy, Waseemen
dc.contributor.authorGorman, Terryen
dc.contributor.authorHussain, Tariqen
dc.contributor.authorArmour-Chélu, Daviden
dc.contributor.authorDeng, Tongen
dc.contributor.authorBradley, Michael Samuel Arthuren
dc.date.accessioned2016-04-15T14:19:24Zen
dc.date.available2016-04-15T14:19:24Zen
dc.date.issued2016-03-15en
dc.identifier.citationEvaluation studies of a sensing technique for electrostatic charge polarity of pharmaceutical particulates 2016 IET Science, Measurement & Technologyen
dc.identifier.issn1751-8822en
dc.identifier.issn1751-8830en
dc.identifier.doi10.1049/iet-smt.2015.0194en
dc.identifier.urihttp://hdl.handle.net/2436/605453en
dc.description.abstractElectrostatic charge due to inter-particle and particle-wall contacts may generate significant hazards during the processing of particulates within the pharmaceutical industry. Although charge behaviour of particulates is erratic and not easy to predict, it would be desirable to characterise the tendency of tribocharging prior to manufacturing. The work reported in this paper concentrates on a new and novel techniques for the detection of the active ingredient and excipient in a bipolar material. Three different case studies are presented for demonstration of the applicability of the method in different practical situations. Work confirmed through an experimental rig set-up indicates that materials that accumulate opposite charge via contact and rubbing can be detected from their charge sign as well as their relative magnitude. The results reported clearly demonstrated that the developed method for charge characterisation is a useful tool to understand how the charges are distributed in a population of particles showing a number of advantages over conventional methods.en
dc.language.isoenen
dc.publisherIET Digital Libraryen
dc.relation.urlhttp://digital-library.theiet.org/content/journals/10.1049/iet-smt.2015.0194en
dc.rightsArchived with thanks to IET Science, Measurement & Technologyen
dc.subjectcharge measurementen
dc.subjectsensorsen
dc.subjectmeasurementen
dc.titleEvaluation studies of a sensing technique for electrostatic charge polarity of pharmaceutical particulatesen
dc.typeArticleen
dc.identifier.journalIET Science, Measurement & Technologyen
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