2.50
Hdl Handle:
http://hdl.handle.net/2436/30253
Title:
Acid phosphatases.
Authors:
Bull, H.; Murray, Paul G.; Thomas, David G.; Fraser, A. M.; Nelson, Paul N.
Other Titles:
Demystified - Acid Phosphatases
Abstract:
Acid phosphatases (APs) are a family of enzymes that are widespread in nature, and can be found in many animal and plant species. Mystery surrounds the precise functional role of these molecular facilitators, despite much research. Yet, paradoxically, human APs have had considerable impact as tools of clinical investigation and intervention. One particular example is tartrate resistant acid phosphatase, which is detected in the serum in raised amounts accompanying pathological bone resorption. This article seeks to explore the identity and diversity of APs, and to demonstrate the relation between APs, human disease, and clinical diagnosis.
Citation:
Molecular Pathology, 55(2): 65-72
Publisher:
BMJ Publishing Group Ltd.
Journal:
Molecular Pathology
Issue Date:
2002
URI:
http://hdl.handle.net/2436/30253
PubMed ID:
11950951
Additional Links:
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1187150&rendertype=abstract
Type:
Article
Language:
en
ISSN:
1366-8714
Appears in Collections:
Molecular Immunology Research Group

Full metadata record

DC FieldValue Language
dc.contributor.authorBull, H.-
dc.contributor.authorMurray, Paul G.-
dc.contributor.authorThomas, David G.-
dc.contributor.authorFraser, A. M.-
dc.contributor.authorNelson, Paul N.-
dc.date.accessioned2008-06-20T10:26:38Z-
dc.date.available2008-06-20T10:26:38Z-
dc.date.issued2002-
dc.identifier.citationMolecular Pathology, 55(2): 65-72en
dc.identifier.issn1366-8714-
dc.identifier.pmid11950951-
dc.identifier.urihttp://hdl.handle.net/2436/30253-
dc.description.abstractAcid phosphatases (APs) are a family of enzymes that are widespread in nature, and can be found in many animal and plant species. Mystery surrounds the precise functional role of these molecular facilitators, despite much research. Yet, paradoxically, human APs have had considerable impact as tools of clinical investigation and intervention. One particular example is tartrate resistant acid phosphatase, which is detected in the serum in raised amounts accompanying pathological bone resorption. This article seeks to explore the identity and diversity of APs, and to demonstrate the relation between APs, human disease, and clinical diagnosis.en
dc.language.isoenen
dc.publisherBMJ Publishing Group Ltd.en
dc.relation.urlhttp://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1187150&rendertype=abstracten
dc.subjectTartrate Resistant Acid Phosphataseen
dc.subjectEnzymesen
dc.subject.meshAcid Phosphataseen
dc.subject.meshBiological Markersen
dc.subject.meshBone Resorptionen
dc.subject.meshFavismen
dc.subject.meshGaucher Diseaseen
dc.subject.meshHumansen
dc.subject.meshIntracellular Fluiden
dc.subject.meshIsoenzymesen
dc.subject.meshLeukemia, Hairy Cellen
dc.subject.meshMaleen
dc.subject.meshOsteoclastsen
dc.subject.meshOsteoporosisen
dc.subject.meshProstateen
dc.subject.meshProstatic Neoplasmsen
dc.subject.meshProtein Bindingen
dc.subject.meshReactive Oxygen Speciesen
dc.subject.meshAlpha-Macroglobulinsen
dc.titleAcid phosphatases.en
dc.title.alternativeDemystified - Acid Phosphatasesen
dc.typeArticleen
dc.identifier.journalMolecular Pathologyen

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