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Wolverhampton Intellectual Repository and E-Theses > Research Institutes > Research Institute in Healthcare Science > Cancer Research Group > Drug resistance in malignant brain tumours

Please use this identifier to cite or link to this item: http://hdl.handle.net/2436/29802
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Title: Drug resistance in malignant brain tumours
Authors: Darling, John L.
Citation: In: Sherbet, G.V., The molecular and cellular pathology of cancer progression and prognosis 2006: 409-430
Publisher: Trivandrum, India: Research Signpost
Issue Date: 2006
URI: http://hdl.handle.net/2436/29802
Additional Links: http://www.ressign.com/UserBookDetail.aspx?bkid=305&catid=140#
Abstract: THIS BOOK: Major advances have been made in recent years towards understanding the genetic basis of cancer. The molecular events occurring in cancer growth, invasion and its secondary spread are being continually elucidated. This book focuses on these events, the genetics of the disease, the nature and temporal changes of gene expression, and the deregulation of genetic programmes that lie at the root of cancer progression. The authors, experts in their respective fields, have attempted to link the genetic alterations with the biological behaviour of cancers. The discussions, reasoning and inferences are based on the behaviour of a fairly wide spectrum of human cancer, thus greatly augment the potential applicability and value of the postulates to the study and treatment of the disease. The construction of molecular profiles of progression might lead to the identification of reliable markers and chemotherapeutic targets and in this way aid in the treatment and management of patients. This book presents comprehensive accounts that would be useful to research workers in the fields of cancer biology, genetics and molecular biology, clinical and medical oncologists, and will be of interest also to graduate and post-graduate students.
Type: Book chapter
Language: en
Keywords: Drug resistance
Malignant tumours
Gene Therapy
Oncology
Cancer treatment
Brain Tumours
Resistance
Cancer genetics
Chemotherapeutic targets
Molecular biology
Reliable markers
Cancer progression
Chemotherapy
ISBN: 8177362836
978-8177362831
Appears in Collections: Cancer Research Group

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