2.50
Hdl Handle:
http://hdl.handle.net/2436/29765
Title:
Phytoestrogens: perpetrators or protectors?
Authors:
Martin, Jan H.; Crotty, Stephen; Nelson, Paul N.
Abstract:
Phytoestrogens are estrogen-like substances produced by plants that account for some of the constituents present in vegetation that may be responsible for the health benefits of a diet rich in fruit and vegetables. Phytoestrogens have a plethora of different actions that they are capable of exerting on cellular metabolism. This review will focus on some of the major non-estrogen receptor-mediated cellular effects used by phytoestrogens and will draw attention to the fact that while they may have a number of beneficial effects, particularly in offering a protective effect against some hormone-dependent cancers, such as breast and prostate cancer, they may also have possible unfavorable effects by interfering with the functioning of normal cellular activities such as receptor-mediated signal transduction and DNA replication, as well as being genotoxic, mutagenic and promoting the proliferation of some cancer cells.
Citation:
Future Oncology, 3(3): 307-318
Publisher:
Future Medicine Ltd
Journal:
Future Oncology
Issue Date:
2007
URI:
http://hdl.handle.net/2436/29765
DOI:
10.2217/14796694.3.3.307
PubMed ID:
17547526
Additional Links:
http://www.futuremedicine.com/doi/abs/10.2217/14796694.3.3.307
Type:
Article
Language:
en
ISSN:
1479-6694
Appears in Collections:
Cancer Research Group

Full metadata record

DC FieldValue Language
dc.contributor.authorMartin, Jan H.-
dc.contributor.authorCrotty, Stephen-
dc.contributor.authorNelson, Paul N.-
dc.date.accessioned2008-06-10T11:03:11Z-
dc.date.available2008-06-10T11:03:11Z-
dc.date.issued2007-
dc.identifier.citationFuture Oncology, 3(3): 307-318en
dc.identifier.issn1479-6694-
dc.identifier.pmid17547526-
dc.identifier.doi10.2217/14796694.3.3.307-
dc.identifier.urihttp://hdl.handle.net/2436/29765-
dc.description.abstractPhytoestrogens are estrogen-like substances produced by plants that account for some of the constituents present in vegetation that may be responsible for the health benefits of a diet rich in fruit and vegetables. Phytoestrogens have a plethora of different actions that they are capable of exerting on cellular metabolism. This review will focus on some of the major non-estrogen receptor-mediated cellular effects used by phytoestrogens and will draw attention to the fact that while they may have a number of beneficial effects, particularly in offering a protective effect against some hormone-dependent cancers, such as breast and prostate cancer, they may also have possible unfavorable effects by interfering with the functioning of normal cellular activities such as receptor-mediated signal transduction and DNA replication, as well as being genotoxic, mutagenic and promoting the proliferation of some cancer cells.en
dc.language.isoenen
dc.publisherFuture Medicine Ltden
dc.relation.urlhttp://www.futuremedicine.com/doi/abs/10.2217/14796694.3.3.307en
dc.subjectCanceren
dc.subjectDieten
dc.subjectNonestrogen receptor mechanismsen
dc.subjectPhytoestrogensen
dc.subject.meshHumansen
dc.subject.meshNeoplasmsen
dc.subject.meshPhytoestrogensen
dc.subject.meshPhytotherapyen
dc.titlePhytoestrogens: perpetrators or protectors?en
dc.typeArticleen
dc.identifier.journalFuture Oncologyen

Related articles on PubMed

All Items in WIRE are protected by copyright, with all rights reserved, unless otherwise indicated.