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Wolverhampton Intellectual Repository and E-Theses > School of Health & Wellbeing > Centre for Health and Social Care Improvement > Diode laser cyclophotocoagulation: role in the management of refractory pediatric glaucomas.

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Title: Diode laser cyclophotocoagulation: role in the management of refractory pediatric glaucomas.
Authors: Kirwan, James F.
Shah, Peter
Khaw, Peng T.
Citation: Ophthalmology, 109 (2): 316-323
Publisher: Elsevier Science Direct
Journal: Ophthalmology
Issue Date: 2002
DOI: 10.1016/S0161-6420(01)00898-3
PubMed ID: 11825816
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Abstract: PURPOSE: To report the efficacy and complications of diode laser cyclophotocoagulation (cyclodiode) in the management of refractory pediatric glaucomas. DESIGN: Noncomparative interventional case series. PARTICIPANTS: Pediatric patients with uncontrolled glaucoma. Seventy-seven eyes of 61 patients underwent cyclodiode. Mean age was 7.4 years (range, 0.4-17 years). MAIN OUTCOME MEASURES: Intraocular pressure (IOP), visual acuity, complications. RESULTS: Diagnoses included aphakic glaucoma, congenital glaucoma, juvenile chronic arthritis, aniridia, anterior segment dysgenesis, and Sturge-Weber syndrome. Sixty percent of eyes were aphakic, and 64% had undergone at least one previous surgical procedure for glaucoma. Patients underwent a mean of 2.3 treatment sessions per eye (maximum, 8 sessions). Mean pretreatment IOP was 32.0 mmHg. After one treatment session, 62% had a clinically useful reduction in IOP (<22 mmHg or by 30%), but this had fallen to 37% by 12 months. With repeat cyclodiode, 72% had a clinically useful reduction in IOP for a year or more (mean, 8.4-month interval between treatments). Aphakic eyes had a more sustained IOP reduction (P < 0.01 log rank test). Of treatment failures, 13% had no useful IOP response, and three eyes developed subsequent retinal detachment and loss of vision. No other eyes lost vision because of cyclodiode-related complications. In 5.5% of the treatment sessions there was a significant posttreatment inflammatory episode. Cyclodiode treatment did not enable a reduction in the number of medications. CONCLUSIONS: With repeated treatment, cyclodiode can provide effective control of IOP. However, the success rate is lower than with adults, and younger eyes may recover from treatment more rapidly. Although response may be temporary, cyclodiode has a lower rate of severe adverse effects than surgical modalities and has roles as a temporizing measure, as an adjunct to surgery, or in managing selected patients in whom surgery is undesirable because of a high risk of surgical complications.
Type: Article
Language: en
MeSH: Adolescent
Age Distribution
Age Factors
Aphakia, Postcataract
Child, Preschool
Ciliary Body
Cohort Studies
Intraocular Pressure
Laser Coagulation
Postoperative Complications
Treatment Outcome
Visual Acuity
ISSN: 0161-6420
Appears in Collections: Centre for Health and Social Care Improvement

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