A brief exposure to moderate passive smoke increases metabolism and thyroid hormone secretion.

2.50
Hdl Handle:
http://hdl.handle.net/2436/22856
Title:
A brief exposure to moderate passive smoke increases metabolism and thyroid hormone secretion.
Authors:
Metsios, Giorgos S.; Flouris, Andreas D.; Jamurtas, Athanasios Z.; Carrillo, A.E.; Kouretas, Dimitris; Germenis, A.E.; Gourgoulianis, K.; Kiropoulos, T.; Tzatzarakis, M.N.; Tsatsakis, A.M.; Koutedakis, Yiannis
Abstract:
CONTEXT: Active smoking influences normal metabolic status and thyroid function. OBJECTIVE: The objective was to assess experimentally the effects of 1 h of moderate passive smoking in a controlled simulated bar/restaurant environment on the metabolism and thyroid hormone levels in healthy nonsmokers. PARTICIPANTS: Eighteen (nine females, nine males) healthy individuals (mean +/- sd: age, 25.3 +/- 3.1 yr; height, 174.0 +/- 10.1 cm; weight, 65.2 +/- 13.7 kg) participated in the study. DESIGN: In repeated-measures randomized blocks, participants visited the laboratory on 2 consecutive days. In the experimental condition, they were exposed to 1 h of moderate passive smoking at a carbon monoxide concentration of 23 +/- 1 ppm in an environmental chamber, whereas in the control condition participants remained in the same chamber for 1 h breathing normal atmospheric air. MAIN OUTCOME MEASURES: In both conditions, cotinine serum and urine levels, resting energy expenditure (REE), as well as concentration of T3, free T4, and TSH were assessed before participants entered the chamber and immediately after their exit. Heart rate and blood pressure were tested in 10-min intervals during all REE assessments. RESULTS: The mean +/- sd difference of serum and urine cotinine levels (-0.27 +/- 3.94 vs. 14.01 +/- 6.54 and 0.05 +/- 2.07 vs. 7.23 +/- 3.75, respectively), REE (6.73 +/- 98.06 vs. 80.58 +/- 120.91) as well as T3 and free T4 (0.05 +/- 0.11 vs. 0.13 +/- 0.12 and 0.02 +/- 0.15 vs. 0.22 +/- 0.20) were increased in the experimental compared with the control condition at baseline and follow-up (P < 0.05). No statistically significant variation was observed in the mean difference of the remaining parameters (P > 0.05). Serum and urine cotinine values were linearly associated with REE (P < 0.05). CONCLUSION: One hour of passive smoking at bar/restaurant levels is accompanied by significant increases in metabolism and thyroid hormone levels.
Citation:
The Journal of Clinical Endocrinology and Metabolism, 92 (1): 208-11
Publisher:
The Endocrine Society/HighWire Press
Journal:
The Journal of Clinical Endocrinology and Metabolism
Issue Date:
2007
URI:
http://hdl.handle.net/2436/22856
DOI:
10.1210/jc.2006-0762
PubMed ID:
17077134
Additional Links:
http://jcem.endojournals.org/
Type:
Article
Language:
en
ISSN:
0021-972X
Appears in Collections:
Sport, Exercise and Health Research Group; Exercise and Health

Full metadata record

DC FieldValue Language
dc.contributor.authorMetsios, Giorgos S.-
dc.contributor.authorFlouris, Andreas D.-
dc.contributor.authorJamurtas, Athanasios Z.-
dc.contributor.authorCarrillo, A.E.-
dc.contributor.authorKouretas, Dimitris-
dc.contributor.authorGermenis, A.E.-
dc.contributor.authorGourgoulianis, K.-
dc.contributor.authorKiropoulos, T.-
dc.contributor.authorTzatzarakis, M.N.-
dc.contributor.authorTsatsakis, A.M.-
dc.contributor.authorKoutedakis, Yiannis-
dc.date.accessioned2008-04-10T09:17:25Z-
dc.date.available2008-04-10T09:17:25Z-
dc.date.issued2007-
dc.identifier.citationThe Journal of Clinical Endocrinology and Metabolism, 92 (1): 208-11en
dc.identifier.issn0021-972X-
dc.identifier.pmid17077134-
dc.identifier.doi10.1210/jc.2006-0762-
dc.identifier.urihttp://hdl.handle.net/2436/22856-
dc.description.abstractCONTEXT: Active smoking influences normal metabolic status and thyroid function. OBJECTIVE: The objective was to assess experimentally the effects of 1 h of moderate passive smoking in a controlled simulated bar/restaurant environment on the metabolism and thyroid hormone levels in healthy nonsmokers. PARTICIPANTS: Eighteen (nine females, nine males) healthy individuals (mean +/- sd: age, 25.3 +/- 3.1 yr; height, 174.0 +/- 10.1 cm; weight, 65.2 +/- 13.7 kg) participated in the study. DESIGN: In repeated-measures randomized blocks, participants visited the laboratory on 2 consecutive days. In the experimental condition, they were exposed to 1 h of moderate passive smoking at a carbon monoxide concentration of 23 +/- 1 ppm in an environmental chamber, whereas in the control condition participants remained in the same chamber for 1 h breathing normal atmospheric air. MAIN OUTCOME MEASURES: In both conditions, cotinine serum and urine levels, resting energy expenditure (REE), as well as concentration of T3, free T4, and TSH were assessed before participants entered the chamber and immediately after their exit. Heart rate and blood pressure were tested in 10-min intervals during all REE assessments. RESULTS: The mean +/- sd difference of serum and urine cotinine levels (-0.27 +/- 3.94 vs. 14.01 +/- 6.54 and 0.05 +/- 2.07 vs. 7.23 +/- 3.75, respectively), REE (6.73 +/- 98.06 vs. 80.58 +/- 120.91) as well as T3 and free T4 (0.05 +/- 0.11 vs. 0.13 +/- 0.12 and 0.02 +/- 0.15 vs. 0.22 +/- 0.20) were increased in the experimental compared with the control condition at baseline and follow-up (P < 0.05). No statistically significant variation was observed in the mean difference of the remaining parameters (P > 0.05). Serum and urine cotinine values were linearly associated with REE (P < 0.05). CONCLUSION: One hour of passive smoking at bar/restaurant levels is accompanied by significant increases in metabolism and thyroid hormone levels.en
dc.language.isoenen
dc.publisherThe Endocrine Society/HighWire Pressen
dc.relation.urlhttp://jcem.endojournals.org/en
dc.subject.meshAdulten
dc.subject.meshCotinineen
dc.subject.meshEnergy Metabolismen
dc.subject.meshFemaleen
dc.subject.meshHumansen
dc.subject.meshMaleen
dc.subject.meshThyroid Hormonesen
dc.subject.meshThyroxineen
dc.subject.meshTobacco Smoke Pollutionen
dc.subject.meshTriiodothyronineen
dc.titleA brief exposure to moderate passive smoke increases metabolism and thyroid hormone secretion.en
dc.typeArticleen
dc.identifier.journalThe Journal of Clinical Endocrinology and Metabolismen

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