|Title: ||Uniform and prolonged changes in blood oxidative stress after muscle-damaging exercise|
|Citation: ||In vivo, 21: 877-884|
|Publisher: ||International Institute of Anticancer Research|
|Journal: ||In vivo|
|Issue Date: ||2007 |
|Abstract: ||Background: The effect of eccentic exercise on the time-course changes in several indices of muscle damage and blood oxidative stress as examined. Materials and methods: Isometric rorque, delayed-onset muscle soreness, creatine kinase, reduced glutathione (GSH), oxidized glutathione (GSSG), thiobarbituric-acid reactive substances (TBARS), protein carbonyls, catalase, uric acid, bilirubin and total antioxidant capacity (TAC) in blood were measured pre-, 24 h, 48 h and 72 h post-exercise of knee extensors in ten females. Results: The concentration of all oxidative stress indices changed significantly in a way indicating increased oxidative stress in the blood (GSH and GSH/GSSG, decreased, whereas GSSG, TBARS, protein carbonyls, catalase, uric acid, bilirubin and TAC increased) peaking, in all but TBARS, at 48 h and returning towards baseline afterwards. Conclusion: We believe that muscle-damaging exercise should be viewedd as a different challenge compared to non-muscle-damaging exercise with regard to its effects on blood oxidative stress.|
|Keywords: ||Free radicals|
Delayed onset muscle soreness
Reactive oxygen species
|Appears in Collections: ||Sport, Exercise and Health Research Group|
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