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Wolverhampton Intellectual Repository and E-Theses > Research Institutes > Research Institute in Healthcare Science > Sport, Exercise and Health Research Group > Uniform and prolonged changes in blood oxidative stress after muscle-damaging exercise

Please use this identifier to cite or link to this item: http://hdl.handle.net/2436/111444
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Title: Uniform and prolonged changes in blood oxidative stress after muscle-damaging exercise
Authors: Paschalis, Vassilis
Nikolaidis, Michalis G.
Fatouros, Ioannis
Giakas, Giannis
Koutedakis, Yiannis
Karatzaferi, Christina
Kouretas, Dimitris
Jamurtas, Athanasios Z.
Citation: In vivo, 21: 877-884
Publisher: International Institute of Anticancer Research
Journal: In vivo
Issue Date: 2007
URI: http://hdl.handle.net/2436/111444
Abstract: Background: The effect of eccentic exercise on the time-course changes in several indices of muscle damage and blood oxidative stress as examined. Materials and methods: Isometric rorque, delayed-onset muscle soreness, creatine kinase, reduced glutathione (GSH), oxidized glutathione (GSSG), thiobarbituric-acid reactive substances (TBARS), protein carbonyls, catalase, uric acid, bilirubin and total antioxidant capacity (TAC) in blood were measured pre-, 24 h, 48 h and 72 h post-exercise of knee extensors in ten females. Results: The concentration of all oxidative stress indices changed significantly in a way indicating increased oxidative stress in the blood (GSH and GSH/GSSG, decreased, whereas GSSG, TBARS, protein carbonyls, catalase, uric acid, bilirubin and TAC increased) peaking, in all but TBARS, at 48 h and returning towards baseline afterwards. Conclusion: We believe that muscle-damaging exercise should be viewedd as a different challenge compared to non-muscle-damaging exercise with regard to its effects on blood oxidative stress.
Type: Article
Language: en
Keywords: Free radicals
Delayed onset muscle soreness
Reactive oxygen species
Redox status
Eccentric exercise
ISSN: 0258-851x
Appears in Collections: Sport, Exercise and Health Research Group

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