Uniform and prolonged changes in blood oxidative stress after muscle-damaging exercise

2.50
Hdl Handle:
http://hdl.handle.net/2436/111444
Title:
Uniform and prolonged changes in blood oxidative stress after muscle-damaging exercise
Authors:
Paschalis, Vassilis; Nikolaidis, Michalis G.; Fatouros, Ioannis; Giakas, Giannis; Koutedakis, Yiannis; Karatzaferi, Christina; Kouretas, Dimitris; Jamurtas, Athanasios Z.
Abstract:
Background: The effect of eccentic exercise on the time-course changes in several indices of muscle damage and blood oxidative stress as examined. Materials and methods: Isometric rorque, delayed-onset muscle soreness, creatine kinase, reduced glutathione (GSH), oxidized glutathione (GSSG), thiobarbituric-acid reactive substances (TBARS), protein carbonyls, catalase, uric acid, bilirubin and total antioxidant capacity (TAC) in blood were measured pre-, 24 h, 48 h and 72 h post-exercise of knee extensors in ten females. Results: The concentration of all oxidative stress indices changed significantly in a way indicating increased oxidative stress in the blood (GSH and GSH/GSSG, decreased, whereas GSSG, TBARS, protein carbonyls, catalase, uric acid, bilirubin and TAC increased) peaking, in all but TBARS, at 48 h and returning towards baseline afterwards. Conclusion: We believe that muscle-damaging exercise should be viewedd as a different challenge compared to non-muscle-damaging exercise with regard to its effects on blood oxidative stress.
Citation:
In vivo, 21: 877-884
Publisher:
International Institute of Anticancer Research
Journal:
In vivo
Issue Date:
2007
URI:
http://hdl.handle.net/2436/111444
Type:
Article
Language:
en
ISSN:
0258-851x
Appears in Collections:
Sport, Exercise and Health Research Group

Full metadata record

DC FieldValue Language
dc.contributor.authorPaschalis, Vassilisen
dc.contributor.authorNikolaidis, Michalis G.en
dc.contributor.authorFatouros, Ioannisen
dc.contributor.authorGiakas, Giannisen
dc.contributor.authorKoutedakis, Yiannisen
dc.contributor.authorKaratzaferi, Christinaen
dc.contributor.authorKouretas, Dimitrisen
dc.contributor.authorJamurtas, Athanasios Z.en
dc.date.accessioned2010-09-20T13:20:09Z-
dc.date.available2010-09-20T13:20:09Z-
dc.date.issued2007-
dc.identifier.citationIn vivo, 21: 877-884en
dc.identifier.issn0258-851x-
dc.identifier.urihttp://hdl.handle.net/2436/111444-
dc.description.abstractBackground: The effect of eccentic exercise on the time-course changes in several indices of muscle damage and blood oxidative stress as examined. Materials and methods: Isometric rorque, delayed-onset muscle soreness, creatine kinase, reduced glutathione (GSH), oxidized glutathione (GSSG), thiobarbituric-acid reactive substances (TBARS), protein carbonyls, catalase, uric acid, bilirubin and total antioxidant capacity (TAC) in blood were measured pre-, 24 h, 48 h and 72 h post-exercise of knee extensors in ten females. Results: The concentration of all oxidative stress indices changed significantly in a way indicating increased oxidative stress in the blood (GSH and GSH/GSSG, decreased, whereas GSSG, TBARS, protein carbonyls, catalase, uric acid, bilirubin and TAC increased) peaking, in all but TBARS, at 48 h and returning towards baseline afterwards. Conclusion: We believe that muscle-damaging exercise should be viewedd as a different challenge compared to non-muscle-damaging exercise with regard to its effects on blood oxidative stress.en
dc.language.isoenen
dc.publisherInternational Institute of Anticancer Researchen
dc.subjectFree radicalsen
dc.subjectDelayed onset muscle sorenessen
dc.subjectReactive oxygen speciesen
dc.subjectRedox statusen
dc.subjectEccentric exerciseen
dc.titleUniform and prolonged changes in blood oxidative stress after muscle-damaging exerciseen
dc.typeArticleen
dc.identifier.journalIn vivoen
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