University of Wolverhampton
Browse
Collection All
bullet
bullet
bullet
bullet
Listed communities
bullet
bullet
bullet
bullet
bullet
bullet
bullet
bullet
bullet
bullet
bullet
bullet
bullet

Wolverhampton Intellectual Repository and E-Theses > School of Sport, Performing Arts and Leisure > Research Centre for Sport, Exercise and Performance > Learning and Teaching in Sport, Exercise and Performance > Biological markers of cardiac damage are not related to measures of cardiac systolic and diastolic function using cardiovascular magnetic resonance and echocardiography after an acute bout of prolonged endurance exercise.

Please use this identifier to cite or link to this item: http://hdl.handle.net/2436/107235
    Del.icio.us     LinkedIn     Citeulike     Connotea     Facebook     Stumble it!



Title: Biological markers of cardiac damage are not related to measures of cardiac systolic and diastolic function using cardiovascular magnetic resonance and echocardiography after an acute bout of prolonged endurance exercise.
Authors: Wilson, Mathew
O'Hanlon, R.
Prasad, S.
Oxborough, D.
Godfrey, R.J.
Alpendurada, F
Smith, G.
Wong, J.
Basavarajaiah, S.
Sharma, S.
Nevill, Alan M.
Gaze, David
George, Keith
Whyte, Gregory P.
Affiliation: Research Centre of Sport and Exercise Performance, University of Wolverhampton, Walsall, UK.
Citation: British journal of sports medicine, Published Online First 23 October 2009
Publisher: BMJ Publishing
Journal: British journal of sports medicine
Issue Date: 2010
URI: http://hdl.handle.net/2436/107235
DOI: 10.1136/bjsm.2009.064089
PubMed ID: 19854761
Abstract: Objectives Seventeen male participants (mean (SD) (range): age 33.5 (6.5) years (46-26 years), body mass 80 (9.2) kg (100-63 kg), height 1.81 (0.06) m (1.93- 1.70 m)) ran a marathon to investigate the relationship between systolic function (using cardiac magnetic resonance (CMR)) and diastolic function (using echocardiography) against biomarkers of cardiac damage. Methods Echocardiographic and cardiac troponin I (cTnI)/N-terminal pro-B-type natriuretic peptide (NTproBNP) data were collected 24 h premarathon, immediately postmarathon and 6 h postmarathon. CMR data were collected 24 h premarathon and at 6 h postmarathon. Results Body mass was significantly reduced postmarathon (80 (9.2) vs 78.8 (8.6) kg; p<0.001). There was a significant E/A reduction postmarathon (1.11 (0.34) vs 1.72 (0.44); p<0.05) that remained depressed 6 h postmarathon (1.49 (0.43); p<0.05). CMR demonstrated left ventricular end-diastolic and end-systolic volumes were reduced postmarathon, with a preserved stroke volume. Left ventricular ejection fraction 6 h postmarathon significantly increased (64.4% (4.2%) vs 67.4% (5%); p<0.05). There were significant elevations in cTnI (0.00 vs 0.04 (0.03) mug/l; p<0.05) and NTproBNP (37.4 (24.15) ng/l vs 59.34 (43.3) ng/l; p<0.05) immediately postmarathon. Eight runners had cTnI elevations immediately postmarathon above acute myocardial infarction cutoff levels (>/=0.03 mug/l). No correlations between cTnI/NTproBNP and measures of diastolic function (E, A, E/A, isovolumic relaxation time, E deceleration time and E/E') or measures of systolic function (stroke volume or ejection fraction) were observed immediately postmarathon or 6 h postmarathon. Conclusions Biomarkers of cardiac damage after prolonged exercise are not associated with either systolic or diastolic functional measures.
Type: Article
Language: en
Description: Epub ahead of print
ISSN: 0306-3674
EISSN: 1473-0480
Appears in Collections: Learning and Teaching in Sport, Exercise and Performance

Files in This Item:

There are no files associated with this item.



Related articles on PubMed
bullet
Myocardial function in older male amateur marathon runners: assessment by tissue Doppler echocardiography, speckle tracking, and cardiac biomarkers.
Knebel F, Schimke I, Schroeckh S, Peters H, Eddicks S, Schattke S, Brechtel L, Lock J, Wernecke KD, Dreger H, Grubitz S, Schmidt J, Baumann G, Borges AC
2009 Jul
bullet
Magnetic resonance imaging of myocardial injury and ventricular torsion after marathon running.
Hanssen H, Keithahn A, Hertel G, Drexel V, Stern H, Schuster T, Lorang D, Beer AJ, Schmidt-Trucksäss A, Nickel T, Weis M, Botnar R, Schwaiger M, Halle M
2011 Feb
bullet
Reproducibility and clinical significance of exercise-induced increases in cardiac troponins and N-terminal pro brain natriuretic peptide in endurance athletes.
Scharhag J, Urhausen A, Schneider G, Herrmann M, Schumacher K, Haschke M, Krieg A, Meyer T, Herrmann W, Kindermann W
2006 Jun
bullet
Exercise-induced right ventricular dysfunction and structural remodelling in endurance athletes.
La Gerche A, Burns AT, Mooney DJ, Inder WJ, Taylor AJ, Bogaert J, Macisaac AI, Heidbüchel H, Prior DL
2012 Apr
bullet
Acute cardiac effects of marathon running.
Trivax JE, Franklin BA, Goldstein JA, Chinnaiyan KM, Gallagher MJ, deJong AT, Colar JM, Haines DE, McCullough PA
2010 May
See all 146 articles

All Items in WIRE are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Fairtrade - Guarantees a better deal for Third World Producers

University of Wolverhampton, Wulfruna Street, Wolverhampton, WV1 1LY

Course enquiries: 0800 953 3222, General enquiries: 01902 321000,
Email: enquiries@wlv.ac.uk | Freedom of Information | Disclaimer and copyright | Website feedback | The University as a charity

OR Logo Powered by Open Repository | Cookies