|Title: ||Cardiorespiratory and immune response to physical activity following exposure to a typical smoking environment.|
|Citation: ||Heart,96 (11): 860-4|
|Publisher: ||BMJ Publishing Group|
|Journal: ||Heart (British Cardiac Society)|
|Issue Date: ||2010 |
|PubMed ID: ||20478865|
|Additional Links: ||http://heart.bmj.com/content/96/11/860.full|
|Abstract: ||OBJECTIVE: Millions of non-smokers suffer daily passive smoking (PS) at home or at work, many of whom then have to walk fast for several minutes or climb a few sets of stairs. We conducted a randomised single-blind crossover experiment to assess the cardiorespiratory and immune response to physical activity following PS. DESIGN: Data were obtained from 17 (eight women) non-smoking adults during and following 30 minutes of moderate cycling administered at baseline and at 0 hour, 1 hour and 3 hours following a 1-hour PS exposure set at bar/restaurant PS levels. RESULTS: We found that PS was associated with a 36% and 38.7% decrease in mean power output in men and women, respectively, and that this effect persisted up to 3 hours (p<0.05). Moreover, at 0 hour almost all cardiorespiratory and immune variables measured were markedly reduced (p<0.05). For instance, FEV(1) values at 0 hour dropped by 10.2% in men and 10.8% in women, while IL-5 increased by 59.2% in men and 44% in women, respectively (p<0.05). At 3-hour mean values of respiratory quotient, mean power, perceived exertion, cotinine, FEV(1), IL-5, IL-6 and INFgamma in both sexes, recovery diastolic and mean arterial pressure, IL-4 and TNFalpha in men, as well as percentage predicted FEV(1) in women remained different compared to baseline (p<0.05). Also, some of the PS effects were exacerbated in less fit individuals. CONCLUSION: It is concluded that 1 hour of PS at bar/restaurant levels adversely affects the response to moderate physical activity in healthy non-smokers for at least 3 hours following PS.|
|Appears in Collections: ||Exercise and Health|
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